Preventive Cardiology Guidelines for South Asians

1. Risk Assessment
- South Asians have 2–3 times higher risk of cardiovascular disease (CVD) than other ethnic groups.
- Traditional risk calculators (e.g., ASCVD Risk Score) often underestimate risk.
- ACC/AHA includes South Asian ethnicity as a risk-enhancing factor.
- Coronary Artery Calcium (CAC) scoring is recommended for borderline/intermediate risk adults (Age 40–75).
2. Lifestyle Modification
- Diet: Emphasize plant-based foods, reduce saturated fat, refined carbs, and sweets.
- Exercise: 150 minutes/week moderate or 75 minutes/week vigorous aerobic activity.
- Avoid all tobacco forms (including smokeless tobacco).
- Limit alcohol; increases risk of hypertension and arrhythmia.
3. Lipid Management
- Lower LDL targets recommended: <100 mg/dL for primary prevention, <70 mg/dL for high-risk individuals.
- Use statins as first-line; consider ezetimibe or PCSK9 inhibitors as adjuncts.
4. Hypertension
- Common at lower BMIs and younger ages among South Asians.
- Target blood pressure: <130/80 mmHg.
- Emphasize home BP monitoring, salt reduction, and weight management.
5. Diabetes & Metabolic Syndrome
- Screen early (age 35+ or younger if risk factors present).
- Use HbA1c, fasting glucose, and 2-hour OGTT.
- South Asians prone to insulin resistance and central obesity.
6. Obesity & BMI
- Overweight: BMI >23 kg/m²; Obesity: BMI >25 kg/m² (WHO Asia-Pacific criteria).
- Waist circumference thresholds: >90 cm (men), >80 cm (women).
7. Aspirin Use
- For primary prevention: only if high ASCVD risk and low bleeding risk.
- Strongly recommended for secondary prevention (post-MI, stroke, or stenting).
8. Psychosocial & Cultural Factors
- Address stress, depression, and acculturation issues.
- Use culturally tailored diet and exercise plans.
- Promote community-based programs.
9. Family History & Genetic Factors
- Strong family history of premature CVD is common.
- Screen first-degree relatives of patients with early-onset CVD.
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