Preventive Cardiology Guidelines for South Asians

ChatGPT Image Apr 5, 2025 at 12_26_29 PM

1. Risk Assessment

  • South Asians have 2–3 times higher risk of cardiovascular disease (CVD) than other ethnic groups.
  • Traditional risk calculators (e.g., ASCVD Risk Score) often underestimate risk.
  • ACC/AHA includes South Asian ethnicity as a risk-enhancing factor.
  • Coronary Artery Calcium (CAC) scoring is recommended for borderline/intermediate risk adults (Age 40–75).

2. Lifestyle Modification

  • Diet: Emphasize plant-based foods, reduce saturated fat, refined carbs, and sweets.
  • Exercise: 150 minutes/week moderate or 75 minutes/week vigorous aerobic activity.
  • Avoid all tobacco forms (including smokeless tobacco).
  • Limit alcohol; increases risk of hypertension and arrhythmia.

3. Lipid Management

  • Lower LDL targets recommended: <100 mg/dL for primary prevention, <70 mg/dL for high-risk individuals.
  • Use statins as first-line; consider ezetimibe or PCSK9 inhibitors as adjuncts.

4. Hypertension

  • Common at lower BMIs and younger ages among South Asians.
  • Target blood pressure: <130/80 mmHg.
  • Emphasize home BP monitoring, salt reduction, and weight management.

5. Diabetes & Metabolic Syndrome

  • Screen early (age 35+ or younger if risk factors present).
  • Use HbA1c, fasting glucose, and 2-hour OGTT.
  • South Asians prone to insulin resistance and central obesity.

6. Obesity & BMI

  • Overweight: BMI >23 kg/m²; Obesity: BMI >25 kg/m² (WHO Asia-Pacific criteria).
  • Waist circumference thresholds: >90 cm (men), >80 cm (women).

7. Aspirin Use

  • For primary prevention: only if high ASCVD risk and low bleeding risk.
  • Strongly recommended for secondary prevention (post-MI, stroke, or stenting).

8. Psychosocial & Cultural Factors

  • Address stress, depression, and acculturation issues.
  • Use culturally tailored diet and exercise plans.
  • Promote community-based programs.

9. Family History & Genetic Factors

  • Strong family history of premature CVD is common.
  • Screen first-degree relatives of patients with early-onset CVD.
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